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Ultra-Processed Foods Linked to 'Silent Stroke' Signs in the Brain, Canadian Study Finds

A Canadian study of 8,783 middle-aged adults found that those with the highest ultra-processed food intake were about 40% more likely to show signs of vascular brain injury—so-called silent strokes—on MRI scans, along with higher body and visceral fat. The study shows association, not causation.

Ultra-Processed Foods Linked to 'Silent Stroke' Signs in the Brain, Canadian Study Finds

Chips, Sugary Cereal and Soda: The Hidden Health Concerns

We all enjoy the occasional bag of chips, sugary cereal or can of soda. But a new Canadian study has found a link between eating more ultra-processed foods and signs of vascular brain injury, sometimes described as silent strokes.

The study, published in the Journal of the American Medical Association, examined 8,783 Canadian adults aged 35 to 69 who did not have cardiovascular disease.

What Did the Study Find?

"The main findings that we had was that, in a group of middle-aged Canadians, those who ate more ultra-processed foods tended to have higher levels of body fat, higher levels of visceral fat, which is fat that's buried deep in your abdomen, and a greater likelihood of having signs of vascular brain injury or silent strokes that were detected on MRI scans," said Russell de Souza, an associate professor in the Department of Health Research Methods, Evidence and Impact at McMaster University and one of the study's researchers.

"This was about 40 per cent more likely in people with the highest ultra-processed food intake. So we did not find that people who consumed more ultra-processed foods performed worse on tests of memory, attention or thinking," he added.

On average, people in the highest intake group had 1.7 percentage points more body fat and 5.7 millilitres more visceral fat than those in the lowest group.

What Are Ultra-Processed Foods?

According to de Souza, ultra-processed foods are industrially formulated products that often contain ingredients, additives or processing methods not typically used in home cooking.

  • Minimally processed: an apple.
  • Processed: applesauce with added sugar.
  • Ultra-processed: apple gummies or fruit snacks that we wouldn't make at home.

Other examples include packaged snack foods, sugary breakfast cereals, soft drinks and ready-to-eat frozen meals.

What Are Silent Strokes?

Researchers used MRI scans to identify signs of brain injury, including small areas of tissue damage linked to interrupted blood flow and changes in the brain's white matter. These changes can occur without obvious symptoms and may be associated with a higher risk of future stroke and cognitive decline.

Dr. Sonia Anand, a professor of medicine at McMaster University and a researcher involved in the study, explained what researchers saw on the scans.

"Essentially, when you put an MRI scan up and you look at the findings, we are seeing the same type of findings we would in someone who had a stroke with the symptoms of a stroke, such as slurred speech or paralysis of an arm or leg. So we're seeing those changes, even though participants didn't report stroke-like symptoms," she said.

Association, Not Causation

The study only examined diet and health at one point in time, so it can't prove that ultra-processed foods caused the brain changes.

The association with brain injury was also less consistent than the findings for body fat, and researchers found no significant differences in liver fat or cognitive test performance.

"We don't know directly whether or not these caused the vascular brain injuries that we saw. We don't know the precise biology behind this yet," de Souza said.

Could Brain Changes Appear Before Cognitive Symptoms?

Anand said the lack of measurable differences in thinking or memory does not necessarily mean there is no reason for concern.

"In other studies we've done and in the medical literature, we do see that the more vascular brain injuries you have on MRI, the lower your cognitive score can become," she said.

However, researchers have not established whether the MRI changes observed in this study will lead to cognitive problems or future strokes.

What Can Canadians Do?

De Souza says people can start by making small changes to their diets, rather than trying to eliminate every processed food.

  • Replace sugary drinks with water.
  • Choose whole fruit instead of packaged snacks.
  • Have oatmeal instead of a highly processed breakfast cereal.

"Making some simple changes... makes a difference over time," he said. The goal is not to eat a perfectly unprocessed diet, but to choose more whole foods where possible.

Anand also stressed that people should not feel alarmed by the findings. She says that making healthier choices isn't always just up to the consumer. She suggested clearer food labels, possible taxation of ultra-processed foods and restrictions on marketing these products, particularly to children.

Montrealers Weigh In

The study raises questions about the role ultra-processed foods play in people's diets. In Montreal, residents have their own thoughts.

  • One man believes there should be stronger restrictions: "You can see in European countries, there's a lot of restriction. We should take example on them... the food that we eat is still pretty bad."
  • Another Montrealer said he avoids ultra-processed foods: "They're just not good for you. So if I can eat whole foods instead, it's a better option for me."
  • A woman said she may consume more than she realizes: "I think I do probably consume high processed foods, starting to be more aware of it... you should spend more time looking at the labels."

More Research Needed

For now, researchers say more studies are needed to understand the connection and whether reducing ultra-processed food intake could help protect long-term brain health.

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